Temero Genero

Temero Genero® 60 tablets (30+30) is a unique bioregulatory complex consisting of two powerful modulators for harmonising the immune and neuroendocrine systems. It contains two preparations: Temero (morning modulator) and Genero (evening modulator), which act synchronously to support the pineal gland, thymus, liver, spleen and brain. Developed by the Institute of Bioregulation and Gerontology to improve overall health and active longevity. The combined use of Temero and Genero forms a comprehensive approach to health, supporting immunity, regulating the neuroendocrine system and promoting active longevity.

The pineal gland is a small endocrine gland in the brain that secretes melatonin, a hormone that regulates circadian sleep-wake rhythms. With age, the function of the pineal gland declines and melatonin secretion decreases, leading to sleep disturbances and desynchronisation of circadian rhythms. Melatonin also has antioxidant, immunomodulatory and antitumour effects. Supporting the pineal gland by providing melatonin precursors (tryptophan → 5-HTP → serotonin → melatonin) is critical for health and longevity.

The thymus (thymus gland) is the central organ of the immune system, where T-lymphocytes mature. With age, the thymus atrophies (thymus involution), leading to immunosenescence - age-related decline in immunity. Supporting the thymus with amino acids, minerals, and vitamins helps slow down immune ageing. The spleen is the organ where B lymphocytes mature and old red blood cells are utilised. The liver is the main detoxification organ, which is also involved in plasma protein synthesis and hormone metabolism.

The neuroendocrine system combines the nervous and endocrine systems, regulating the body's homeostasis. The hypothalamic-pituitary axis controls the functioning of the peripheral endocrine glands (thyroid, adrenal glands, gonads). The pineal gland regulates the circadian rhythms of all physiological processes. Disruptions in neuroendocrine regulation lead to insomnia, depression, anxiety, hormonal imbalances, and accelerated ageing. Alcohol and drug addiction severely disrupt neurotransmitter systems - recovery requires nutritional support from neurotransmitter precursors.

Temero is a morning modulator that targets the pineal gland and brain, improving metabolism and supporting liver health. It contains glycine, glutamic acid, choline bitartrate, aspartic acid, calcium, magnesium and zinc citrates, alanine, 5-hydroxytryptophan (5-HTP) and folic acid. These components help activate the brain and maintain emotional balance throughout the day.

The 5-hydroxytryptophan (5-HTP) in Temero is a direct precursor to serotonin, a neurotransmitter that regulates mood, appetite, sleep, and cognitive function. Taking 5-HTP in the morning increases serotonin levels throughout the day, improving mood, reducing anxiety, and increasing stress resistance. Serotonin is also a precursor to melatonin, a pituitary hormone that regulates circadian rhythms and sleep. Adequate serotonin levels during the day ensure normal melatonin synthesis in the evening.

Glycine is the simplest amino acid with multiple functions. It acts as an inhibitory neurotransmitter in the central nervous system, reducing nervous system excitability and improving cognitive function, memory, and concentration. Glycine has a neuroprotective effect, protecting neurons from ischaemia and toxins. It improves sleep, but when taken in the morning, it does not cause drowsiness, but improves performance and clarity of thinking. Glycine is also involved in the synthesis of glutathione, the main antioxidant in the liver, and has a hepatoprotective effect.

Glutamic acid is an excitatory neurotransmitter that stimulates cognitive function, learning, and memory. It participates in the brain's energy metabolism and is a precursor to GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter. The balance of glutamate and GABA is critical for the normal functioning of the nervous system. Aspartic acid is involved in the urea cycle (ammonia detoxification), energy metabolism, and the synthesis of other amino acids. Alanine is a glucogenic amino acid that can be converted into glucose for energy.

Choline bitartrate is a precursor of acetylcholine, a neurotransmitter involved in memory and learning. It also participates in the synthesis of phosphatidylcholine (lecithin), the main phospholipid of cell membranes, especially neurons. Choline is necessary for the transport of fats from the liver, preventing fatty degeneration. Calcium, magnesium and zinc citrates provide bioavailable minerals. Folic acid (vitamin B9) is necessary for the synthesis of neurotransmitters, DNA methylation and the prevention of depression.

Genero is an evening modulator aimed at regenerating and strengthening the immune system. It contains calcium, magnesium and zinc citrates, glutamic and aspartic acids, proline, choline bitartrate, lysine and folic acid. Amino acids and minerals promote recovery during sleep, reduce stress and regulate the nervous system.

Proline is an amino acid that is critical for the synthesis of collagen, which makes up 30% of all proteins in the body and forms skin, bones, cartilage, blood vessels, and connective tissue. Regeneration and repair processes are activated at night, with collagen synthesis being particularly intense during deep sleep. Proline is also involved in energy metabolism and can be converted into glucose. Lysine is an essential amino acid necessary for the synthesis of collagen (together with proline), carnitine (a transporter of fatty acids into mitochondria for energy production), calcium absorption, and immune function.

Magnesium is especially important in the evening - it relaxes muscles, reduces nervous excitability, blocks NMDA glutamate receptors, and improves sleep quality, especially deep (slow-wave) sleep, when the main recovery, growth hormone production, and memory consolidation occur. Calcium is also involved in sleep regulation — it is necessary for the synthesis of melatonin from serotonin. Zinc supports immune function, protein synthesis, healing, and regeneration.

FIELD OF APPLICATION:

• strengthening the immune system
• neuroendocrine disorders
• stimulation of regeneration processes
• sleep disorders, stress, nervousness
• comprehensive correction of depressive disorders
• alcohol and drug addiction treatment programmes
• comprehensive correction of climacteric disorders
• body rejuvenation programmes (active longevity)
• improvement of overall tone and vitality
• chronic fatigue and asthenia
• age-related decline in immunity
• circadian rhythm disorders

ADVANTAGES:

Temero Genero is a unique bioregulatory complex consisting of two powerful modulators for harmonising the immune and neuroendocrine systems, developed by the Institute of Bioregulation and Gerontology. Temero is a morning modulator with 5-hydroxytryptophan (a precursor to serotonin) that improves mood, reduces anxiety, improves stress resistance throughout the day, and ensures melatonin synthesis in the evening.

Glycine reduces excitability, improves cognitive function, memory and concentration, and has neuroprotective and hepatoprotective effects. Glutamic and aspartic acids stimulate cognitive function and energy metabolism. Choline bitartrate is a precursor to acetylcholine for memory and prevents fatty liver disease. Mineral citrates and folic acid support brain metabolism. Targets the pineal gland and brain, improves metabolism, supports liver health, activates the brain, and maintains emotional balance during the day.

Genero is an evening modulator with proline and lysine for collagen synthesis - tissue regeneration is especially active during sleep. Magnesium relaxes muscles, reduces excitability, improves deep sleep and recovery. Calcium is necessary for melatonin synthesis. Zinc supports immunity and regeneration. Targets the thymus and spleen - strengthens the immune system, promotes recovery during sleep, reduces stress and regulates the nervous system.

Combined use provides support for the pineal gland, thymus, liver, spleen, and brain, forming a comprehensive approach to health, supporting immunity, regulating the neuroendocrine system, and promoting active longevity. Ideal for improving health and maintaining high vitality.

ACTIVE COMPONENTS:

Temero (morning): glycine, glutamic acid, choline bitartrate, asparagic acid, calcium citrate, magnesium citrate, zinc citrate, alanine, 5-hydroxytryptophan, folic acid.
Genero (evening): calcium citrate, magnesium citrate, glutamic acid, asparagic acid, proline, choline bitartrate, zinc citrate, lysine, folic acid.

PACKING:

30 tablets by 0.55 g + 30 tablets by 0.65 g / product: Temero Genero / Non-GMO. Not a medical drug.